ppt课件-a d a p t a t i o n t o h i g h a l t i t u d e- powering silicon valley（一个d p t t i o n t o h i g h l t我t u d e -推动硅谷）.pptVIP

下载本文档

8
0
约1.23万字
约 72页
2017-01-25 发布于四川
举报
版权申诉

ppt课件-a d a p t a t i o n t o h i g h a l t i t u d e- powering silicon valley（一个d p t t i o n t o h i g h l t我t u d e -推动硅谷）.ppt

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

SYSTEMATIC O2 TRANSPORT AND DELIVERYFICK EQUATION: VO2 = Q X O2 EXTRACTION OR VO2 = SV X HR X A - V O2 DIFFERENCE ACUTE EXPOSURE DECREASE IN SaO2 AND CaO2 WILL STIMULATE SNS WHICH INCREASES HR AND HENCE Q AT A GIVEN SUBMAXIMAL WORKLOAD; CONSEQUENTLY VO2 AT AN ABSOLUTE WORKLOAD IS MAINTAINED INCREASED CARDIAC OUTPUT (Q) DUE TO INCREASED HR TO MAINTAIN VO2 AT A GIVEN SUBMAXIMAL WORKLOAD HIGH ALTITUDE ADAPTATION RELATED TO: ? CHANGES IN CARDIAC OUTPUT (SV X HR) ? CHANGES IN OXYGEN EXTRACTION (I.E., ARTERIAL - VENOUS OXYGEN DIFFERENCE) HIGH ALTITUDE ADPATATION DECREASED CARDIAC OUTPUT (FIG 13-8) DUE TO A DECREASE IN STROKE VOLUME DECREASE IN Q APPEARS AFTER 48 HOURS AND CONTINUES TO DECREASE FOR 8-9 DAYS ? NATIVE HIGHLANDERS (NH) AND ACCLIMATED LOWLANDERS (AL) BOTH HAVE A SIMILARLY REDUCED Q DECREASE IN CARDIAC OUTPUT IS DUE TO: DECREASE IN RESTING, SUBMAXIMAL, AND MAXIMAL SV DURING FIRST TWO WEEKS OF ALTITUDE ADAPTATION, PLASMA VOLUME DECREASES; BECAUSE OF THE INCREASE IN RBC LEVELS AND THE DECREASE IN PLASMA VOLUME, HEMATOCRIT AND BLOOD VISCOSITY INCREASES; THIS WOULD POTENTIALLY DECREASE CARDIAC OUTPUT DUE TO AN INCREASE IN PERIPHERAL RESISTANCE (Q = P/R) REASONS FOR A DECREASE IN SV: DECREASED CARDIAC FILLING (I.E., EDV), POSSIBLY DUE TO TACHYCARDIA, INCREASED VENTILATION RATE, DECREASED PLASMA VOLUME, AND/OR INCREASED BLOOD VISCOSITY; THE INCREASED VISCOSITY AND DECREASED PLASMA VOLUME MAY DECREASE VENOUS RETURN OF BLOOD FLOW TO THE HEART INCREASED ESV DUE TO DECREASED MYOCARDIAL CONTRACTILITY (FRANK-STARLING LAW NOTE: NATIVE HIGHLANDERS (NH) AND ACCLIMATED LOWLANDERS (AL) BOTH HAVE A SIMILARLY REDUCED Q AS SHOWN PREVIOUSLY IN FIG 13-9 - NATIVE HIGHLANDERS HAVE GREATER SV AND LOWER HR THAN THE ACCLIMATED LOWLANDERS - ACCLIMATED LOWLANDERS HAVE A HIGHER HR AND LOWER SV THAN THE NATIVE HIGHLANDERS ARTERIAL - VENOUS OXYGEN DIFFERENCE (I.E., OXYGEN EXTRACTION) MAXIMAL EXERCISE: A -V O2 DIFFERENCE IS THE SAME OR SLIGHTL