静脉补铁论文.docVIP

重点关注 透析过程中泵前输液器输入与肝素泵静推补铁方法效果比较 解放军第88医院 宋娜 [摘要] 目的 观察慢性肾功能衰竭并发肾性贫血患者在血液透析中种静脉给予蔗糖铁方法的临床效果，例慢性肾功能衰竭维持性血液透析并发肾性贫血的患者随机分为两组各 例，在血液透析过程中分别进行动脉端泵前静脉滴注蔗糖铁和泵蔗糖铁，均为次/周，100mg/次，总剂量mg。 两组患者均常规使用基因重组红细胞生成素治疗，每周剂量为120～200 U/kg，在整个试验过程中保持剂量不变治疗前、治疗结束后周检查两组患者血清铁蛋白、血红蛋白、红细胞压积，并进行比较。两组患者静脉补铁总剂量000 mg 治疗结束后2周，血清铁蛋白、血红蛋白、红细胞压积都较治疗前有明显升高 ，差异有统计学意义 （P＜0.001）；两组患者各指标升高的幅度差异无统计学意义（P＞0.05）动脉端泵前静脉滴注蔗糖铁和泵蔗糖铁都可应用于血液透析中静脉补铁，效果相当，但泵蔗糖铁与使用比较更适合血液透析过程中多例患者同时静脉补铁的应用更能节省护理人力[关键词] 慢性肾功能衰竭； 血液透析； 肾性贫血； 静脉补铁； 血清铁蛋白 Abstract] Objective To observe the effects of two methods for intravenous iron in renal anemia patients undergoing hemodialYsis so as to explore the better method for intravenous iron. Methods 70 patients with chronic renal failure complicated with renal anemia during hemodialYsis were evenlY randomiZed into two groups: intravenous drip of iron sucrose through arterial side of the pump before sucrose infusion pumps and intravenous iron sucrose heparin , twice everY week, 100 mg each time and with a total volume of 1 000 mg. All the patients were treated bY r-HuEpo at a total dosage of 120～200 U/kg all through the course. The serum ferritin, hemoglobin and HCT were tested in the two groups before and two weeks after treatment, and then compared between the groups. Results Compared to pre-treatment, the serum ferritin, hemoglobin and HCT increased significantlY two weeks after that (P0.001), but the increases in the indexes within each group were no significant (P0.05). Conclusion Arterial side of the pump prior to intravenous iron sucrose infusion pumps and intravenous iron sucrose heparin can be applied to intravenous iron in hemodialysis, the effect is quite, but simple intravenous heparin pump iron sucrose method, easy to drop into the empty pipeline caused by air compared with the use of infusion, the process is more suitable for multi-hemodialysis patients and intravenous iron applications, they could save nursing workforce to ensure the safety of dialysis. 【Key words】 chronic re