精神病学3BipolarDisorders.pptVIP

* Bipolar disorders Yao- qian kun Bipolar disorder is a prevalent, disabling, and recurrent psychiatric disease, which until recently was equated with classic manic –depressive illness (i.e. bipolar Ⅰdisorder). Major depressive disorder and bipolar Ⅰdisorder constitute the two major mood disorders in psychiatry. However, bipolar disorder encompasses a much broader range of illnesses than bipolarⅠdisorder. This range of illnesses is often refered to as bipolar spectrum disorders and include bipolar Ⅰ disorder, bipolar Ⅱdisorder ,and other forms of bipolar disorder. In general, bipolar disorder is characterized by a dysregulation of mood and associated risky behavior, impulsivity, and interpersonal problems. Bipolar disorder causes significant impairment in social, occupational, or other important areas of functioning, and may lead to premature mortality through suicide. WHO identified bipolar disorder as the sixth leading cause of disability-adjusted life years (DALY s) in the world among people aged 15-44 years. To sum up, bipolar disorder is a chronic mood disorder that places a significant burden not only on the patients, but also on their families and society in general. Epidemiology The lifetime prevalence rate of bipolar Ⅰdisorder is about 1 percent in western countries, and this is true across almost all social classes, education levels and races. According to WMH-CIDI (World Mental Health-Composite International Diagnostic Interview) surveys, in East Asia and Pacific regions the lifetime prevalence rate of bipolar Ⅰdisorder is 0.1%---0.7%. In Korea, a nation-wide epidemiological study conducted in 2001 showed that the lifetime prevalence rate of this mental illness was 0.4% and, in terms of the number of DALYs caused by neuropsychaitric disorders, bipolar disorder was ranked 5th.However, if the diagnosis of bipolar Ⅱdisorder and other subtypes (mixed or depressed) is included in this calculation, much hig