药物效应动力学-幻灯片1.pptVIP

Chapter 2. Pharmacokinetics (1)To explain the drug action and mechanisms of drug action, and to direct clinical administration; (1)Preclinical pharmacology: ●The object of research: Human being; (1)Source of new drugs: ●Preclinical study(临床前研究) : ▲ Phase Ⅰ(一期临床): 20-30位健康志愿者; Chapter 1. Pharmacodynamics Part 1. Basic action of drug Part 2. Dose-effect relationship Part 3. Mechanism of drug action Part 4. Drug and Receptor 1. Action and effect of drug: (1)Concept of action and effect: ①Action: e.g.: Noradrenaline(NA) stimulat-ing ? receptor of blood vessel ?