自制同种异体皮质骨腰椎间融合器临床应用的中远期随访评价.doc

自制同种异体皮质骨腰椎间融合器临床应用的中远期随访评价 廖壮文、范子文，杨进顺 广州医科大学附属第二医院，骨外科 摘要摘要 目的：探讨自制一体成型式皮质骨生物型腰椎间融合器（Forming one cortical biological lumber fusion cage，FOCBLFC)在腰椎后路椎间融合术的中远期临床疗效，评价其替代金属或碳纤维腰椎椎间融合器在临床应用及椎间融合方面的合理性及有效性。方法： 对获得3年以上随访的18例应用FOCBLFC行腰椎后路椎间融合术的腰椎退行性病变患者进行临床和影像学评估，分析其手术特点、并采用VAS评分及Oswestry功能障碍指数(Oswestry Disability Index，ODI) 价评其术后腰腿痛程度及社会、生活能力情况。同时对比手术后椎高度前凸。术椎间高度。移植移与相结合可以实现稳定椎间高度前凸实现椎融合移植相关并发症:椎间融合，异体骨临床Clinical application of forming one cortical biological lumber fusion cage: medium to long-term follow-up evaluation. /Zhuangwen Liao, Ziwen Fan, Jinshun Yang. /the Second Affiliated Hospital of Guangzhou Medical University. China. Objective: To observe the medium to long-term follow-up clinical outcomes of Forming one cortical biological lumber fusion cage(FOCBLFC) in the posterior lumber interbody fusion and assess its Reasonableness and effectiveness of clinical using and interbody fusion rate as a Substitutes to metal or carbon fiber cage. Methods: 18 patients who obtain over 3-5 years follow-up with lumbar degenerative disease were treated by posterior decompression, implantation of FOCBLFC and pedical screw fixation. The VAS and ODI scoring systems were used for clinical evaluation. The X-ray test was performed pre and post operatively and the movement of spinous process, trabecula of bone, and radiolucent zone were observed. And the intervertebral height and lumbar lordosis changes were monitored so as to explore the fusion cage synostosis. Result: All patients’ low back pain relieved and nerve function restored. There are no significant procedure-related complications. All patients achieved bone fusion within 2 years follow-up period. The intervertebral height and lumbar lordosis the last follow-up were significantly Improved and maintained compared to pre-operation and immediate post-operation. And the FOCBLFC were eventually absorbed and replaced. There are no cases of graft and fixation loosening. Conclusion: FOCBLFC can effectively maintain the physiologic