颅内动脉狭窄流行病学、内科治疗、支架治疗.pptVIP

* * * All patients were placed on aspirin 325 mg daily and loaded with clopidogrel 300 to 600 mg daily with clopidogrel 75 mg daily continued for a minimum of 3 months. After 3 months, aspirin was reduced to 81 mg daily and clopidogrel 75 mg daily was continued unless patients reported cost difficulties or adverse events, at which time they were switched to aspirin monotherapy. 让我们再来看一下2011年国际上最新公布的SAMMPRIS研究结果。该研究是迄今首个前瞻性、随机、由NINDS（美国国立神经疾病与卒中研究院）牵头、比较积极药物治疗和联用支架成形术对症状性颅内动脉严重狭窄预防卒中复发的研究，发表在权威新英格兰杂志上。 * * SAMMPRIS研究人群包含颅内大动脉严重狭窄70-99%导致的发病30天内的非致残性缺血性卒中患者，随机接受积极药物治疗或联合Wingspan支架置入术，其中积极药物治疗组包