食管癌放化疗面临的挑战与对策.pptVIP

食管癌放化疗面临的挑战与对策 蚌医一附院放疗科 李多杰 发病率高 死亡率高 早诊率低 生存率低 2005.1-2006.12，共153例鳞癌，不能手术 3D-CRT 35%同步铂类化疗 中位剂量64GY（50-74GY） 5Y-OS 26.3% 预后因素：GTV和病灶长度 Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer CROSS研究 Chemoradiotherapy for Oesophageal Cancer Followed by Surgery Study Complete resection with no tumor within 1 mm of the resection margins (R0) was achieved in 92% of patients in the chemoradiotherapy–surgery group versus 69% inthe surgery group (P0.001) A pathological complete response was achieved in 47 of 161 patients (29%) who underwent resection after che