新生儿缺氧缺血性脑病早期综合治疗临床分析.docVIP

新生儿缺氧缺血性脑病早期综合治疗临床分析 　　doi：10.3969/j.issn.1007-614x.2014.21.43 　　摘 要 目的：探讨新生儿缺氧缺血性脑病早期综合治疗的临床疗效。方法：2011年2月-2013年6月收治新生儿缺氧缺血性脑病患儿66例，随机分成综合治疗组和对照组各33例，对照组采用传统三支持和三对症方法治疗。综合治疗组在对照组的基础上进行综合治疗。结果：经过治疗，综合治疗组显效22例，有效9例，无效2例，总有效率93.9%；对照组显效15例，有效9例，无效6例，死亡3例，总有效率72.7%，两组比较差异有统计学意义（P0.05）。综合治疗组在治疗6个月、12个月运动和智力评分明显高于对照组，两组比较差异有统计学意义（P0.05）。综合治疗组出现后遗症3例，后遗症发生率9.1%，其中发生脑瘫1例，智力低下1例，听觉障碍1例；对照组出现后遗症8例，后遗症发生率24.2%，其中发生癫痫1例，脑瘫2例，智力低下3例，听觉障碍1例，视觉障碍1例。结论：早期综合疗法治疗早期新生儿缺氧缺血性脑病疗效显著，值得推广。 　　关键词 早期综合治疗 新生儿 缺氧缺血性脑病 　　Clinical analysis of early comprehensive treatment on neonatal hypoxic ischemic encephalopathy 　　Zhou Jinguo 　　The Maternal and Child Care Service Centre of Xianfeng County，Hubei 445600 　　Abstract Objective：To investigate the clinical effect of early comprehensive treatment on neonatal hypoxic ischemic encephalopathy.Methods：66 cases of neonatal hypoxic ischemic encephalopathy were selected from February 2011 to June 2013.They were randomly divided into the treatment group and the control group with 33 cases in each.The control group were given the traditional treatment of three support and three symptomatic.The treatment group were given comprehensive treatment on the basis of the traditional treatment.Results：After treatment，in the treatment group 22 cases of excellence，9 cases of effective，2 cases of invalid，the total efficiency was 93.9%.In the control group 15 cases of excellence，9 cases of effective，6 cases of ineffective，3 cases died，and the total efficiency was 72.7%.The difference was statistically significant between the two groups（P0.05）.Exercise and intelligence score of 6 months and 12 months after treatment in the treatment group was significantly higher than that in the control group.The difference was statistically significant（P0.05）.In the treatment group 3 cases of sequelae，the occurrence rate of sequelae was 9.1%，including 1 cases of cerebral palsy，1 cases of low intelligence，1 cases of hearing impairment.In the control group 8 cases of sequelae，t