早发型重度子痫前期患者终止妊娠时机、方式与妊娠结局的关系探讨.docVIP

早发型重度子痫前期患者终止妊娠时机、方式与妊娠结局的关系探讨 　　[摘要] 目的 探讨不同妊娠时机、妊娠方式对早发型重度子痫前期患者以及妊娠结局的影响。 方法 回顾性分析本院收治的181例早发型重度子痫前期患者的临床资料，根据发病孕周的不同分为A组（发病孕周28周）、B组（28周≤发病孕周32周）、C组（发病孕周≥32周），并根据患者分娩方式不同分为阴道分娩组与剖宫产组，比较不同组别间围生儿的结局以及孕产妇并发症发生率。 结果 A组孕产妇并发症发生率、围生儿死亡率、围生儿并发症发生率显著高于B、C组（P0.05）；阴道分娩组孕产妇并发症发生率、围生儿死亡率、围生儿并发症发生率显著高于剖宫产组（P0.05）。 结论 早发型重度子痫前期患者发病孕周越早，围生儿死亡率越高，应当给予期待治疗延长孕周，并采用剖宫产以降低孕产妇并发症发生率及围生儿的死亡率。 　　[关键词] 早发型重度子痫前期；终止妊娠；妊娠结局 　　[中图分类号] R714.24+5 [文献标识码] A [文章编号] 1674-4721（2014）08（b）-0059-03 　　[Abstract] Objective To investigate the impact of termination time，way and pregnancy outcome in patients with early onset severe preeclampsia and fetal outcome of pregnancy. Methods The clinical data of 181 cases early onset severe preeclampsia was retrospectively analyzed in our hospital，which were divided into group A （onset of gestational age28 weeks），group B （28 weeks≤onset of gestational age32 weeks），group C （onset of gestational age≥32weeks），according to the incidence of gestational age and were divided into group and cesarean group and vaginal delivery group accordordint to mode of delivery.Perinatal outcomes and maternal child morbidity were compared between different groups. Results The maternal complication rate，perinatal mortality，perinatal complication rate of group A were significantly higher than group B and group C （P0.05），maternal complication rate，perinatal mortality，perinatal complication rate of cesarean group were significantly higher than cesarean group （P0.05）. Conclusion The earlier the age of onset severe preeclampsia gestational，the perinatal death rate is higher，should give to extend gestational weeks treatment，and the use of cesarean delivery in order to reduce the maternal complications and perinatal mortality. 　　[Key words] Early onset severe preeclampsia；Termination of pregnancy；Pregnancy outcomes 　　早发型重度子痫前期（early onset severe preeclampsia，ESOP）患者终止妊娠的时机与方式对于孕产妇及胎儿的妊娠结局有很大影响，临床医师在处理ESOP时，面临着胎儿不成熟与延长孕周风险间的矛盾[1]。本研究主要探讨不同妊娠时机、妊娠方式对ESOP患者以及胎儿妊娠结局的影响。 　　1 资料与方法