第十二章真核基因表达调控.ppt

四、M 期检测点 M 期检测点又叫纺锤体组装检测点。主要是阻止细胞分裂、阻止细胞两极形成纺锤体、阻止染色体附着到纺锤体上。 细胞周期检测点功能的减弱，会导致突变基因的累积和遗传的不稳定性，但只有当累积的突变基因破坏了细胞周期驱动机制时，细胞才能进入失控性生长。 12.3 发育的基因调节 视频： DNA时代.01 来源：NHK * The activity of a regulatory transcription factor may be controlled by synthesis of protein, covalent modification of protein, ligand binding, or binding of inhibitors that sequester the protein or affect its ability to bind to DNA. * The homeodomain of the Antennapedia gene represents the major group of genes containing homeoboxes in Drosophila; engrailed (en) represents another type of homeotic gene; and the