分子生物学2课件1.pptVIP

Fully functional and species-specific SL1 can be reconstituted from these purified components. TAFIs and TAFIIs could compete with each other for binding to TBP. This finding suggested that the binding of one set of TAFs to TBP is mutually exclusive of binding of the other set. The TBP is identical in the two factors but the TAFs are completely different. These TAFs are completely different from those found in TFIID. 2) Upstream-Binding Factor-UBF This transcription factor is an assembly factor that helps SL1 to bind to the core promoter element. The factor was composed of two polypeptides, o