Ophthalmic Pathology midatlanticpas眼科病理 midatlanticpas.pptVIP

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Ophthalmic Pathology midatlanticpas眼科病理 midatlanticpas.ppt

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Ophthalmic Pathology midatlanticpas眼科病理 midatlanticpas

Conjunctival Cases Case 1 * * * * * * * * * * * * Ophthalmic Pathology Emiko Furusato, M.D. Department of Neuropathology and Ophthalmic PathologyArmed Forces Institute of Pathology A joint conference with MAPA and PANE 2009 Contents Grossing the globe Ocular histology 10 Representative cases Grossing the ocular specimen Four basic steps Orient the specimen and determine laterality Measurements Transillumination (TI) Sectioning the globe Grossing the ocular specimen Anatomic landmarks that orient the specimen Cornea: Horizontal meridian is wider Long posterior ciliary vessels: Blue line marks horizontal meridian posteriorly Inferior oblique: Inferotemporal quadrant, nasal end near fovea, no tendon Superior oblique: Superiorly and temporally, shiny tendinous insertion 1. Orient the specimen and determine laterality Posterior aspect of left eye Temporal side Nasal side Long ciliary vessel Optic nerve Vortex vein Inferior oblique muscle Superior oblique muscle Posterior aspect of right eye Temporal side Nasal side Nasal side Inferior oblique muscle Superior oblique muscle Optic nerve Long ciliary vessels Anterior aspect of right eye Nasal side Temporal side Horizontal diameter :11 mm Vertical diameter: 10mm Grossing the ocular specimen Globe: AP (antero-posterior including the cornea), Horizontal, Vertical, length of the optic nerve Normal eye (24 mm = one inch) in diameter Cornea: Horizontal and vertical planes 12 (horizontal) x11mm (vertical) or 11X10mm. Diameter of pupil Note dimensions of any lesions such as wounds, tumors, etc 2. Measurements Grossing the ocular specimen 3.Transillumination (TI) Grossing the ocular specimen Transilluminated prior to dissection. Use dissecting microscope illuminator in a darkened room. Applications Uveal malignant melanoma Dark shadow on the sclera 3.Transillumination (TI) Pupil Dark band of ciliary body Pigmented tumor show round shadow Ciliochroidal melanoma Retinal detachment Lens Ciliary body O