Oxidative Phosphorylation and Electron Transport 氧化磷酸化与电子输运.pptVIP

Oxidative Phosphorylation and Electron Transport Chain(ETC) What is phosphorylation? What is Oxidative phosphorylation? Formation of ATP from coupling of ADP and Pi is known as phosphorylation. Three types- (1) Substrate level phosphorylation (2) Photophosphorylation (3) Oxidative phosphorylation (1) Substrate level phosphorylation Enzymatic Transfer of phosphate from substrate to ADP to form ATP. ATP made in glycolysis and the TCA cycle is the result of substrate- level phosphorylation (2) Photophosphorylation Formation of ATP in light reaction of photosynthesis. In which photosynthetic organisms capture the energy of sunlight—the ultimate source of energy in the biosphere and harness it to make ATP Photophosphorylation involves the oxidation of H2O to O2, with NADP as ultimate electron acceptor; it is absolutely dependent on the energy of light. Oxidative phosphorylation How cells convert the stored metabolic energy of NADH and [FADH2] into ATP? NADH or FADH2-dependent ATP synthesis is the result of oxidative phosphorylation.i. e. Formation of ATP from the oxidation of NADH or FADH2 in presence of oxygen through electron transport chain is know as oxidative phosphorylation. Oxidative phosphorylation is the collection of energy yielding metabolism in aerobic organisms. All oxidative steps in the degradation of carbohydrates, fats, and amino go through this final stage of cellular respiration, in which the energy of oxidation drives the synthesis of ATP Electrons stored in the form of the reduced coenzymes, NADH or [FADH2], are passed through an elaborate and highly organized chain of proteins and coenzymes, therefore called electron transport chain, finally reaching O2 (molecular oxygen) is the terminal electron acceptor. Each component of the chain can exist in (at least) two oxidation states, and each component is successively reduced and reoxidized as electrons move through the chain from NADH (or [FADH2]) to O2. In the course of electron tra