Rimonabant in Obesity Clinical Trial Results在肥胖的临床试验结果利莫那班.pptVIP

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Rimonabant in Obesity Clinical Trial Results在肥胖的临床试验结果利莫那班.ppt

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Rimonabant in Obesity Clinical Trial Results在肥胖的临床试验结果利莫那班

History of Angioplasty and PCI Devices 3000 B.C. – Ultra-thin metal pipes employed by Egyptians to perform bladder catheterizations 400 B.C. – Hollow reeds and pipes used as catheters to study function of cardiac valves in cadavers 1711 – Hales performs the first cardiac catheterization on a horse using brass pipes, a glass tube and the trachea of a goose 1844 – French physiologist Bernard coins the term “cardiac catheterization” and employs catheters to record intra-cardiac pressures in animals 1929 – Dr. Werner Forssmann performs the first documented human cardiac catheterization in Germany 1941 – Two physicians at Columbia University, André Cournand and Dickinson Richards, use the cardiac catheter as a diagnostic tool to measure cardiac output 1956 – Forssmann, Richards and Cournand receive the Nobel Prize with Cournand noting that the “cardiac catheter was. . . the key in the lock.” 1958 – Dr. Mason Sones of the Cleveland Clinic conducts an imaging procedure of a child’s aortic valve, accidentally engaging the right coronary artery and injecting dye. When the patient’s heart did not display the expected fibrillation, Sones realized he had discovered the key to selective imaging of the heart – the diagnostic coronary angiogram. History of Angioplasty and PCI Devices 1964 – Dr. Charles Dotter with Dr. Melvin Judkins introduces the concept of remodeling arteries, known as transluminal angioplasty, by applying the earlier findings to open blocked peripheral arteries with atherosclerosis 1967 – Dr. Rene Favaloro performs the first saphenous vein graft (bypass) surgery 1967 – Judkins creates his own system of diagnostic imaging, introducing a series of specialized catheters and perfecting the transfemoral approach (introducing the catheter via a groin puncture rather than the more complex procedure used by Sones of introducing the catheter via surgical opening of the brachial artery in the arm) 1974 – Dr. Andreas Gruentzig performs the first human periphe