刺五加片联合黛力新治疗PCI术后焦虑症的临床研究.docVIP

刺五加片联合黛力新治疗PCI术后焦虑症的临床研究 　　[摘要] 目的 观察刺五加片联合黛力新对经皮冠状动脉介入治疗（PCI术）后焦虑症患者的临床疗效。 方法 选取我院收治确诊的PCI术后焦虑症患者80例，随机分为治疗组和对照组各40例，对照组采用黛力新治疗，治疗组在口服黛力新基础上加用刺五加片，两组均治疗8周后，进行治疗前、治疗后汉密尔顿焦虑量表（HAMA）评价。 结果 治疗组、对照组总有效率分别为95.0%，87.5%，差异具有统计学意义（P0.05），治疗组HAMA评分下降幅度优于对照组（P0.05）。 结论 刺五加片联合黛力新可明显改善PCI术后患者焦虑症的症状，提高患者生活质量。 　　[关键词] 刺五加片；黛力新；PCI术；焦虑症 　　[中图分类号] R743.3 [文献标识码] B [文章编号] 1673-9701（2016）17-0126-03 　　Clinical study on acanthopanax root tablets combined with deanxit in treatment of post-PCI anxiety 　　FAN Aide LI Xiamei 　　Department of Cardiology， Changde First Traditional Chinese Medicine Hospital in Hunan Province， Changde 415000，China 　　[Abstract] Objective To observe the clinical effect of acanthopanax root tablets combined with Deanxit in treatment of post-percutaneous coronary intervention （PCI） anxiety. Methods 80 patients with post-PCI anxiety treated in our hospital were selected and randomly divided into treatment group and control group， each had 40 cases. The control group was treated by Deanxit， and the treatment group was additionally given acanthopanax root tablets. The patients were evaluated by HAMA before treatment and after 8 weeks of treatment. Results The overall response rate were 95.0% and 87.5% respectively in the treatment group and the control group， and the difference was significant（P0.05）. The reduction of HAMA scores was significantly more in the treatment group than in the control group（P0.05）. Conclusion Combination of acanthopanax root tablets and Deanxit can significantly relieve the post-PCI anxiety and improve the life quality of patients. 　　[Key words] Acanthopanax root tablet； Deanxit； PCI； Anxiety 　　据世界卫生组织统计，冠心病是目前全球导致死亡的最常见原因，是人类健康的头号“杀手”[1]，目前，经皮冠状动脉介入治疗（PCI术）是目前冠心病，特别是急性心肌梗死的主要治疗方法之一，由于PCI术具有手术创伤小、诊断快捷明确、治疗效果显著等特点，受到临床广泛应用，但由于患者有过胸痛经历、对PCI术缺乏充分了解、术后长期服药、害怕复发等原因，导致相当一部分PCI术后患者易罹患焦虑症，对临床疗效、远期预后造成严重影响。研究表明，临床中31%～40%胸部不适症状的患者是由焦虑症所致[2，3]，多表现为随紧张情绪、天气变化，甚至莫名的心慌、胸闷等，可自行缓解或安慰缓解消失，反复发作。并且冠心病与焦虑症之间互为因果，相互影响，共同导致临床病情加重[4]，甚至器质性病变。2006年我国著名