盐酸利托君对112例早产胎膜早破新生儿结局的影响.docVIP

盐酸利托君对112例早产胎膜早破新生儿结局的影响 　　[摘要] 目的 探讨盐酸利托君对早产胎膜早破新生儿结局的影响。 方法 回顾分析112例早产胎膜早破孕妇及其新生儿的临床资料，随机分为观察组和对照组，观察组用硫酸镁治疗，对照组用盐酸利托君治疗。比较两组新生儿Apgar 1 min及5 min评分、新生儿肺炎、败血症、呼吸窘迫综合征的发生率。 结果 对照组新生儿Apgar 1 min及5 min评分平均略低于观察组新生儿评分，但组间比较差异均无统计学意义（P0.05）；观察组的新生儿肺炎、败血症、呼吸窘迫综合征发生率明显低于对照组，两组比较差异有统计学意义（P0.05）。 结论 盐酸利托君在早产胎膜早破的治疗中疗效明显，可以减少新生儿并发症的发生，值得在临床广泛使用。 　　[关键词] 早产；胎膜早破；盐酸利托君；新生儿结局 　　[中图分类号] R714.4 [文献标识码] B [文章编号] 1673-9701（2016）25-0054-04 　　Effects of ritodrine hydrochloride on neonatal outcomes in 112 premature infants with premature rupture of membrane 　　YUAN Chaojun 　　Department of Gynecology and Obstetrics， Nanchang Third Hospital， Nanchang 330009， China 　　[Abstract] Objective To discuss the effects of ritodrine hydrochloride on the neonatal outcome in premature infants with premature rupture of membrane. Methods Clinical data of 112 cases of pregnant women delivering premature infants with premature rupture of membrane and their newborns were retrospectively analyzed. They were randomly assigned to the observation group and the control group. The observation group was given magnesium sulfate for treatment， and the control group was given ritodrine hydrochloride for treatment. 1-minute and 5-minute Apgar scores， incidence rates of neonatal pneumonia， septicemia and respiratory distress syndrome were compared between the two groups of newborns. Results 1-minute and 5-minute Apgar scores in the control group were slightly lower than those in the observation group， but the differences between groups were not statistically significant（P0.05）； the incidence rates of neonatal pneumonia， septicemia and respiratory distress syndrome were significantly lower than those in the control group， and the differences between groups were statistically significant （P0.05）. Conclusion Ritodrine hydrochloride in the treatment of premature rupture of membrane has significant curative effects， which is able to reduce the incidence rate of neonatal complications and is worthy of widespread