芍倍注射液治疗Ⅰ~Ⅱ度直肠脱垂30例的近远期疗效和安全性观察.docVIP

芍倍注射液治疗Ⅰ~Ⅱ度直肠脱垂30例的近远期疗效和安全性观察 　　摘 要 目的：探讨芍倍注射液治疗Ⅰ～Ⅱ度直肠脱垂的近远期疗效和安全性。方法：将我院2012年1月―2016年6月收治的60例Ⅰ～Ⅱ度直肠脱垂患者，随机分为A、B两组各30例。A组给予消痔灵注射液治疗，B组给予芍倍注射液治疗，随访6个月，比较两组患者近远期疗效，安全性指标，并发症等情况。结果：两组患者近期疗效相近，无统计学意义（P0.05）；两组均有个别患者出现腹部坠痛，且血常规、肝肾功能等有所改变，无显著差异（P0.05）；B组患者复发率低于A组 （4.45% vs 25.13%），总有效率高于A组患者（P0.05）而局部并发症发生率低于A组（P0.05）。结论：芍倍注射液对Ⅰ～Ⅱ度直肠脱垂远期治疗疗效明显，并发症少，复发率低，安全，可靠。 　　关键词 芍倍注射液 直肠脱垂 疗效 　　中图分类号：R286； R574.63 文献标识码：B 文章编号：1006-1533（2016）21-0030-03 　　Short and long-term efficacy and safety of Shaobei injection in the treatment of 30 cases of rectal prolapse 　　ZHAO Chunquan（Department of General Surgery， Maternal and Child Health Care Hospital of Duchang County， Duchang 524272， China） 　　ABSTRACT Objective： To explore the safety and curative effect of Shaobei injection in the treatment of rectal prolapse. Methods： Sixty cases of patients with rectal prolapse were randomly divided into group A and B with 30 case each. Group A and B were treated with Xiaozhiling injection or Shaobei injection， respectively and followed up for 6 months， and the short and long-term efficacy， safety index， and incidence of complications were compared between two groups. Results： There was similar efficacy between two groups （P0.05）. The abdominal falling pain and some changes of the indexes of blood routine tests and liver and kidney function appeared only in the individual patient （P0.05）. The recurrence rate was lower in group B than in group A （4.45% vs 25.13%）， and the total efficiency was higher while the local incidence of complications was lower in the group B than in group A （P0.05）. Conclusion： Shaobei injection has clear efficacy in the long-term treatment of I ～ II degrees of rectal prolapse and is safe and reliable with less complications and lower recurrence rate. 　　KEY WORDS Shaobei injection； rectal prolapse； efficacy 　　直肠脱垂是肛肠外科的一种疾病，指直肠、肛管、甚至部分乙状结肠移位下降和外脱。各年龄阶段的人都可以发病，但多发于幼儿、老年人、久病体弱及身高瘦弱者。而女性因骨盆下口较大及多次分娩等因素，发病率高于男性。直肠脱垂常见于中老年女性，最常见的症状是便秘和排空障碍，使患者非常痛苦[1]。临床中，用手术治疗直肠脱垂，引起了很多的