细胞4,细胞膜与细胞表面-课件.pptVIP

In many cases, one can use proteases to cut the loops of the polypeptide chain that link the transmembrane a helices one either side of the bilayer and the helices stay together and function normally. In some cases, one can even express engineered genes encoding separate pieces of a multipass protein in living cells, and one finds that the separate pieces assemble properly to form a functional transmembrane protein, emphasizing the exquisite specificity with which transmembrane a helices can interact. In this example functional Na+-K+ ATPase molecules are purified and incorporated into phosp