Relation between ABO blood groups and Helicobacter pylori infection in symptomatic patients.pptVIP

Relation between ABO blood groups and Helicobacter pylori infection in symptomatic patients Mohamad Salih Jaff Clinical and Experimental Gastroenterology 2011:4 221–226 Fooyin University student：Shu-Wan Chine 2011.12.22 Introduction The association of ABO blood groups with some infectious and noninfectious diseases has been described. Mourant AE, et al., 1978 and Jaff MS, et al., 1987 History of Helicobacter Family not yet named (17 species by rRNA sequencing) First observed in 1983 as Campylobacter-like organisms in the stomachs of patients with type B gastritis. Nomenclature of Helicobacter was first established in 1989. Important Human Pathogens Helicobacter pylori -is major human pathogen associated with gastric antral epithelium in patients with active chronic gastritis. Helicobacter cinaedi Helicobacter fenneliae Before Helicobacter pylori identification as the main etiology of peptic ulcers, chronic gastritis, and a variety of gastrointestinal symptoms. Marshall BJ, 1986 and Tytgat GNJ, et al., 1990 and Rosenstock S, et al., 1997 Many epidemiologic studies had found that nonsecretors of ABO blood group antigens and individuals of blood group O were overrepresented among patients with peptic ulcers. Aird I, et al., 1953 and Clark CA, et al., 1956 and Boren T, et al., 1993 Many methods are used in clinical practice to diagnose H. pylori infection, including measurement of serum immunoglobulin G (IgG) antibodies by enzyme-linked immunosorbent assay (ELISA) and Helisal rapid blood (HRB) test. Evans DJ Jr, et al., 1989 Aim： To verify the incidence of seropositive H. pylori infection among patients with dyspepsia symptoms. To verify the frequencies of ABO blood groups in H. pylori seropositive symptomatic patients. Subjects and Methods From February 2010 to March 2011