用扫描质子微探针研究地砷病区人发中微量元素的分布.pdfVIP

咿同地方病防治杂志 2007 年第 22 卷第 6 期 Chin J C衍I Endem Die VoJ. 22 No.6 2007 .407. 用扫描质子微探针研究地呻病区人发中微量元素的分布 杨瑞瑛 1 ，张智勇 1 ，正庆暴2 ，朱节清z {摘要 1 目的 研究地方性碑中毒(地仰病)病底改良饮用水前后病妇头发中碑及其他微量元素含量的变化，确定 改水对病妇体内呻及其他微量元素的影响。方法 用扫描质子徽探针测定病妇单根头发中硝及其他 10 种微量元素的 含暨分布。结果 发现 As 、Fe 、 Cu 、 Ni 、 Mn 、 Ti 、 Sr 、 K 在地畔病茧病人头发中平均含最最高，轻病人次之，正常人最低;而 Ca 和 Zn 在健康人头发中浓度最高。重病人、轻病人发根与发梢上潘 7 种元素食肇若是异显著 ( p 0.05 或 P 0.001) 。 综论 地碑病区对改水减硝工程大大降低了病人体内的确食巅，促进了微镜元素的代谢平衡。 {关键诩] 扫描质子微探针;地方性仰中吉普;头发;微最元索 中阁分类寄 :R 599.9 文献标识码 :A 文章编号: 1001 -1889 (2007) 侃而0407 -03 Study of Trace Elemental Distribution in Hair of Endemic Arsenism Patient Using Scanning Proton Microprobe YANG Ru? - yi吨 I ZHANG Zhi 叩 yo吨 I W ANG Qing - ji I et a1 (Key Lab07aωry 01 Nuclear Analysis Tech叫脯， lnstítUle 01 High Energy Ph庐山， The Chinese Acαdemy 01 Scienc时， Beijing 1倒附) [ Abstract] 0时ective In order 10 know the effecls of improving water in endemic arsenism area on concentratíons of As and other trace elements in human body , distributions of arsenic and other lrace elements in single ha?r of female patíents who have been drinkíng improved water for one year were studíed. Methods The concentrations of 11 elements in síngle haír of seri- ous and minor endemic arsenísm female patients were determined by scanníng proton mícroprohe (SPM). ResulωThe highest concentratíons of As. Fe , Cu , K, Mn , Ni , Sr , and Ti were found in serious endemic arsenism group , while the lowest contents of these elements were found in normal control group. The concen tration of Ca and Zn were highest in healthy people haír. There were extremely significant differences ín contents of he above rnentioned el制nents ( P 0.05 07 P 0.001). Conclusions Improvíng drinkíng water is an effectíve w且y for reducing As in patient bodies. Meanwhile , homeostasis of other trace elements were maíntaíned. [Key words] Scanníng proton mícroprobe (SPM) j Endemíc arsen?s川 Hair i Trace elements 头发作为人体新陈代谢的重要排油途径之…，其 中微最元素含量与人体接触的外部环境、膳食情况及 这些元素在人体内的负荷情况等有密切的关系，在一 定条件下可用来评估这些元素的环境暴露露及