重叠综合症解决方案.ppt

A C O S;材料来源;Main teaching points;引言;ACOS;Phenotype of COPD ?;Prevalence of ACOS;;Different criteria different outcome;Burden of ACOS;Fattahi F. Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study.Respir. Res. 2013; 14: 10.;;Chung JW, Kong KA, Lee JH, Lee SJ, Ryu YJ, Chang JH. Characteristics and self-rated health of overlap syndrome. Int. J. Chron. Obstruct. Pulmon. Dis. 2014; 9: 795–804.;PATHOPHYSIOLOGY OF ACOS;Gene;;;;Cigarette smoking can alter airway inflammation in asthma from being eosinophilic toneutrophilic with increased CD8+ cells, thus becoming similar to that seen in COPD.;Step-wise approach to diagnosing ACOS;Asthma ACOS;;COPD ACOS;Avaliable features;Recall bias Lack of lung function testing typical symptoms and respond to ICS;GINA and GOLD. Diagnosis of diseases of chronic airflow limitation:asthma, COPD and asthma-COPD overlap syndrome(ACOS) (updated 2015). Available from URL: http:///. Accessed: 13 April 2015.;;Sputum Eosinophil Counts;;;Management ;;Individualized management;Disability;Future ACOS Studies;Conclusions;谢谢