Analysisof287Patients_省略_actorsinaSingle.pdf

J Huazhong Univ Sci Technol［Med Sci］ 31(1):2011 107 Analysis of 287 Patients with Aortic Dissection: General Characteristics, Outcomes and Risk Factors in a Single Center Guofu HU (胡国富), Bi JIN (金 毕), Hong ZHENG (郑 鸿), Chuanshan LAI (赖传善), Chenxi OUYANG (欧阳晨曦), Yin XIA (夏 印), Yiping DANG (党一平), Yiqing LI (李毅清)# Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China ? Huazhong University of Science and Technology and Springer-Verlag Berlin Heidelberg 2011 Summary: The general characteristics, outcomes and risk factors of the patients with aortic dissection (AD) were evaluated in a single medical center. From January 2002 to December 2008, 284 patients with AD were treated and followed-up at our institution, including 105 cases of type A AD and 179 cases of type B AD. The patients in each type were divided into three groups according to management: medical treatment group (A or B), open surgery group (A or B), and stent-graft group (A or B). The characteristics and follow-up outcomes were compared between the groups or subgroups. The results showed that there was significant difference in the prognosis for type A AD between medical treatment group and open surgery group, but there was no significant difference in the prognosis for type B AD between medical treatment group and stent-graft group. Independent risk factors of follow-up mortality for patients with type A AD included a history of atherosclerosis (HR, 3.807; 95% confidence interval [CI], 1.489 to 7.611; P=0.003), in-hospital hypotension/shock (HR, 4.687; 95% CI, 1.846 to 11.900; P=0.001), in-hospital myocardial ischemia or infarction (HR, 3.734; 95% CI, 1.613 to 8.643; P=0.002), pleural effusion (HR, 2.210; 95% CI, 1.080 to 4.521; P=0.030), branch vessel involvement (HR, 2.747; 95% CI, 1.202 to 6.278; P=0.016) and surgical treatment (HR, 0.177; 95% CI, 0.063 to 0.502; P=0.001). And