Tei、BNP联合筛选急性冠脉综合征高危患者的临床研究.doc

Tei Index and B-Type Natriuretic Peptide in Assessment of High-risk Patients with Acute Coronary Artery Syndromes GAO-XING ZHANG, XUE-FANG ZHANG, BIAO-CHEN, ZHAO-XIN LAI, RU-MING LIN, YU-CHENG PENG, WEI-DONG GAO, QIANG-REN, JUN-XING LAI, AN-JIAN SONG, YAN-HUA SUN From Jiangmen Central Hospital, Sun Yat-Sen University, Guangdong Province, Jiangmen 529030, China ZHANG ET AL.: Tei Index and B-Type Natriuretic Peptide in Assessment of High-risk Patients with Acute Coronary Artery Syndromes. to assess the value of Doppler echocardiographic Tei index and B-Type natriuretic peptide (BNP) in evaluating high-risk patients with acute coronary artery syndromes and their relationship with myocardial ischemia. Eighty-three consecutive patients and eighty controls were included, according to ACC/AHA directions, patients were divided into low-risk group and high-risk group, all participants had undergone echocardiography, neurohormonal analysis, coronary angiography, Gensini score were recorded. All data were analysised by SPSS 13.0 software. The results showed that tei index and BNP were higher in pateints with acute coronary artery syndromes, and the difference between low-risk group and high-risk group was still significantly. they were independent predictors of myocardial ischemia, and were useful in assessing high-risk patients with acute coronary artery syndromes. Tei Index, B-Type natriuretic peptide, Acute coronary artery syndromes 摘要： 探討超聲多普勒指標－Tei指數與血漿腦利鈉肽（BNP）評估急性冠脈綜合征高危患者及二者與心肌缺血的關係。連續入選83例急性冠脈綜合征患者，80例健康者作為對照組，根據ACC/AHA指南，將急性冠脈綜合征患者分為低危組和高危組，所有入選者均行超聲心動圖檢查，血漿BNP濃度測定，冠狀動脈造影，並記錄Gensini積分。所有資料採用SPSS13.0統計軟體進行分析。結果顯示：Tei指數和BNP在急性冠脈綜合征患者顯著升高，且低危組與高危組之間也有顯著差別，二者是心肌缺血的獨立預測因數，對評估急性冠脈綜合征高危患者一定價值。 Address for reprints: Dr. Gao-Xing Zhang Jiangmen Central Hospital, Sun Yat-Sen University, Guangdong Province, Jiangmen 529030, China Tel:Email: sdfeixue81@163.com The study was supported by science and technology research institution Jiangmen, Guangdong, China Intr