TRISODIUMCITRATE-柠檬酸三钠.pdfVIP

TRISODIUM CITRATE Prepared at the 19th JECFA (1975), published in NMRS 55B (1976) and in FNP 52 (1992). Metals and arsenic specifications revised at the 59th JECFA (2002). An ADI not limited was established at the 17th JECFA (1973) SYNONYMS Sodium citrate; INS No. 331(iii) DEFINITION Chemical names Trisodium citrate, trisodium salt of 2-hydroxy-1,2,3- propanetricarboxylic acid, trisodium salt of ?-hydroxy-tricarballylic acid C.A.S. number 68-04-2 Chemical formula Anhydrous: C6H5Na3O7 Hydrated: C6H5Na3O7 · xH2O Structural formula Formula weight 258.07 (anhydrous) Assay Not less than 99.0% calculated on the dried basis DESCRIPTION Colourless, odourless crystals, or white, crystalline powder; hydrated forms available include the dihydrate and the pentahemihydrate FUNCTIONAL USES Buffer, sequestrant, emulsion stabilizer CHARACTERISTICS IDENTIFICATION Solubility (Vol. 4) Freely soluble in water, insoluble in ethanol Test for citrate To 5 ml of a 1 in 10 solution of the sample add 1 ml of calcium chloride TS and 3 drops of bromothymol blue TS, and slightly acidify with dilute hydrochloric acid TS. Add sodium hydroxide TS until the colour changes to a clear blue, then boil the solution for 3 min, agitating gently during the