1,6-diphosphate treatment of severe neonatal hypoxic ischemic encephalopathy 49 cases Observation.docVIP

 PAGE \* MERGEFORMAT 7 1,6-diphosphate treatment of severe neonatal hypoxic ischemic encephalopathy 49 cases Observation Of: Luo Hongbin, Liu Shulan, Liao Zhiwei [Abstract] Objective To observe 1,6-diphosphate (FDP treatment of severe neonatal hypoxic ischemic encephalopathy (HIE effect. Methods A case-control study, the 97 patients with moderate to severe HIE were randomly divided into treatment group and control group The control group received conventional treatment group on the basis of conventional therapy plus treatment with 1,6-diphosphate, the clinical efficacy and 14 d after the inspection head CT, were statistically analyzed. Results The total treatment group efficiency of 89.90%, significantly better than the control group 64.58% (χ2 = 8.78, P lt;0.005, head CT examination was significantly higher than normal rate of 82.22% 57.14% (χ2 = 6.52, P lt;0.025. conclusions on the basis of conventional therapy plus 1,6-diphosphate treatment can significantly improve the efficacy of moderate to severe HIE. [Keywords:] neonatal hypoxic ischemic encephalopathy, 1,6-diphosphate, efficacy Neonatal hypoxic ischemic encephalopathy (HIE is due to fetal distress, neonatal asphyxia caused by a common central nervous system of neonatal System lesions, moderate and severe HIE is an important cause of disability of children. Our hospital 1,6-diphosphate (FDP treatment of severe neonatal HIE 49 patients achieved good effect, are as follows. 1 Materials and Methods 1.1 General information on neonatal hypoxic ischemic encephalopathy based diagnostic criteria and clinical classification of degrees [1], to January 2003 ~ April 2008 newborn inpatient hospital treatment of 97 patients with moderate to severe HIE were randomly divided into treatment group and control group patients were in the age of 3 days cranial CT. the treatment group 49 patients, 26 males and 23 females, gestational age (38.3 + -2.7 weeks, birth weight lt;2 500 g 5 cases, 2 500 ~ 4 000