147 inpatients respiratory tract Candida infection Identification and analysis of drug resistance.docVIP

 PAGE \* MERGEFORMAT 8 147 inpatients respiratory tract Candida infection Identification and analysis of drug resistance Author: Zhou Xiao-Ming Zi Wo Anthony Pool [Keywords:] candida;, fungal identification;, drug analysis,, Abstract: The purpose of the respiratory tract Candida isolated were identified and do analysis of drug resistance. Methods Kema Jia chromogenic medium for separation of 147 Candida strains to identify and use Rosco commercialization of drug-resistant paper analysis. The results of respiratory tract infection with Candida albicans-based (755%), non-Candida albicans infections on the rise. Amphotericin, nystatin resistance was the lowest, respectively, 61%, 34%, followed by itraconazole (170%), the highest rate of fluconazole resistance (571%), Candida krusei is resistant strong Candida, followed by Candida glabrata, Candida tropicalis; non-Candida albicans Candida albicans, compared with the resistance rates were significantly different (P = 0000). 387% of the Candida or 2 more than two kinds of antifungal drug resistance. Conclusion respiratory tract Candida infection on the rise, should enhance the detection and drug-resistant Candida analysis. Keywords: Candida; fungi identification; drug resistance analysis In recent years, with extensive use of broad-spectrum antibiotics, cancer chemotherapy, organ transplants carried out, as well as the increase in immunocompromised patients, from deep fungal opportunistic infections caused by the increasing, especially common in respiratory tract specimens. Patients often have severe underlying diseases, and long-term use of antibiotics, or because of certain pathogenic Candida infections continue to increase, but also makes the treatment of drug-resistant fungal problems have become increasingly prominent. We are in June 2003 ~ November 2004 separation of 147 respiratory tract Candida strains and antimicrobial susceptibility results of retrospective analysis, are reported below. 1 Materials an