4 cases of uterine sarcoma cancer clinical pathologic analysis and review of literature.docVIP

 PAGE \* MERGEFORMAT 10 4 cases of uterine sarcoma cancer clinical pathologic analysis and review of literature [Abstract] Objective To investigate the clinical pathology of uterine carcinosarcoma features, pathological diagnosis and differential diagnosis. Methods of 4 cases of uterine sarcoma cancer Histopathological and immunohistochemical detection. The results of light microscopy, 4 cases of uterine carcinosarcoma were visible specific cancer and sarcoma components, cancer are endometrial adenocarcinoma, 1 case of sarcoma composed of leiomyosarcoma, 2 cases of sarcoma composed of endometrial stromal sarcoma, 1 case of sarcoma composed of endometrial stromal sarcoma and smooth muscle sarcoma. immunohistochemistry: cancer region of cytokeratin (CK) positive leiomyosarcoma region vimentin (Vim-positive, actin (actin)-positive, desmin (desmin positive, endometrial stromal [Keywords:] cancer, uterine sarcoma immunohistochemistry Uterine carcinosarcoma is a rare malignant tumor, malignant tumors in the uterus, accounting for about 5% [1]. Mainly occurs in middle-aged women, and occasionally in children and young women. It has both malignant epithelial component also has room The vicious nature of the composition, are not sensitive to chemotherapy and radiotherapy, the prognosis is poor. In this paper, four cases of uterine sarcoma in patients with cancer, clinical manifestations, pathology and immunohistochemical characteristics were observed and analyzed to discuss the clinical pathological characteristics and to provide The pathological diagnosis and differential diagnosis. 1 Materials and methods Collection of the First Affiliated Hospital of Liaoning Medical College clinical data between 2007-2008, a complete surgical resection specimens of four cases of uterine cancer sarcoma. Specimens were fixed in 10% formalin, paraffin embedding, HE staining. And by SP immunohistochemical method: cytokeratin (CK), vimentin (Vim), CD10, muscle actin (actin