A34 glycoprotein expression in gastric changes in the evolution of.docVIP

 PAGE \* MERGEFORMAT 12 A34 glycoprotein expression in gastric changes in the evolution of [Abstract] Objective: To explore the A34 in gastric glycoprotein expression of the evolution and clinical significance. Methods: RT PCR method detected 18 cases of normal gastric mucosa, respectively (A group, 30 cases of chronic atrophic gastritis (B, 24 cases of early gastric mucosa (C group and 48 cases of advanced gastric mucosa (D group glycoprotein A34 mRNA expression. immunohistochemical method to detect the expression of glycoprotein A34. Results: glycoprotein A34 mRNA in normal tissue, atrophic gastritis, early gastric cancer and advanced gastric cancer relative expression levels were 0.093 + -0.010, 0.211 + -0.023, 0.258 + -0.017, 0.259 + -0.021, sugar, protein expression was positive in all groups A34 rates were 5.56%, 33.33%, 70.83%, 75.00%. A34 glycoprotein and its mRNA expression in A, B, C between the three groups were statistically significant differences (P lt;0.05), early and advanced gastric cancer gastric cancer was no significant difference between the two groups (Pgt; 0.05). Conclusion: A34 glycoprotein in gastric expression of the evolution of gradually strengthening. [Keywords:] gastric cancer, glycoprotein A34, reverse transcription polymerase chain reaction, immunohistochemistry [Abstract] Objective: To investigate the expression of glycoprotein A34 in the development of gastric carcinoma and discuss their relations with clinical significance.Methods: The expression of glycoprotein A34 mRNA and protein was detected by RT PCR and immunohistochemical technique in 18 healthy volunteers (group A), 30 patients with chronic atrophic gastritis (group B), 24 patients with early gastric carcinoma (group C), and 48 patients with advanced gastric carcinoma (group D). Results: The expression of glycoprotein A34 mRNA were 0.093 + -0.010 , 0.211 + -0.023, 0.258 + -0.017 and 0.259 + -0.021, in normal, chronic atrophic gastritis, early gastric carcinoma