Affect the long-term prognosis of renal transplant the main factor.docVIP

 PAGE \* MERGEFORMAT 16 Affect the long-term prognosis of renal transplant the main factor Keywords:: kidney transplantation; Prognosis; donor How to improve the long-term prognosis of renal transplantation and the donor increased by increasing the number of renal transplantation, kidney transplantation is now facing two major problems. This article briefly describes the impact long-term prognosis of renal transplant the main factor, and may help to overcome some of the measures of donor shortage. Impact of a long-term prognosis of renal transplant the main factor Affect the long-term prognosis of renal transplantation many factors, the most important factors, including [1 ~ 3]: 1.1 Effects of the U.S. transplant centers one pairs of more than 27,000 cases of cadaveric renal transplantation retrospective study showed that: different transplant centers, the one-year survival rate of transplanted kidney from 52% to 100%, graft half-life (a graft half-life) from 3 years to 25 years. Now that the transplant center effect is affecting prognosis of renal transplantation the most important factor, second only to fellow between HLA identical twin effect of transplantation on graft. 1.2 receptor (patient) age recently, the European Dialysis Transplant Association report, 20 patients with renal transplantation under the age of 5-year survival rate was significantly lower than other age groups. It was also reported in patients over the age of 55 kidney transplant survival in patients with less than 15 ~ 54 years old. Children with lower graft survival rate, mainly due to rejection compared with the frequent and serious-related; kidney transplantation in elderly patients with poor prognosis, the higher mortality rate related with the elderly. 1.3 receptors in the body namely, the existence of preoperative antibody levels in sensitized kidney transplant patients is larger the number of lymphocytotoxicity antibodies, after transplantation the greater the likelihood of