Analysis of Mycobacterium tuberculosis resistant to multiple drugs.docVIP

 PAGE \* MERGEFORMAT 13 Analysis of Mycobacterium tuberculosis resistant to multiple drugs [Abstract] Objective In recent years, the growing problem of TB drug resistance, and drug-resistant TB epidemic in China has become one of the most serious, so to do in order to better prevention and treatment of TB, Mycobacterium tuberculosis on isoniazid hydrazine and rifampicin resistance, to provide a theoretical basis for the clinical. Methods test is the use of drugs containing a certain concentration of LJ medium detected in the clinic in 2009 application of automated BACTEC MGIT 960 culture-positive Mycobacterium detector of 381 Mycobacterium tuberculosis to isoniazid (INH) and rifampicin (RFP) for drug resistance. Results 381 Mycobacterium tuberculosis resistant to isoniazid (INH) and rifampicin (RFP) are 48, accounting for about 12.6%. Conclusions high incidence of drug-resistant tuberculosis, the TB incidence of refractory, thus affecting TB control and elimination, but also increases the cost of treatment. [Keywords:] Mycobacterium tuberculosis; isoniazid; rifampicin; susceptibility test Mycobacterium tuberculosis called Mycobacterium tuberculosis, TB is the human and animal pathogens, including human Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium Africa and the voles and other mycobacteria, the first three human pathogenic bacteria, which were Mycobacterium tuberculosis infection in the highest incidence. Mycobacterium tuberculosis is a zoonotic infection caused by the serious infectious diseases, but also the single pathogen infections of human mortality in the highest bacterial infections [1,2]. Medical research shows that whether the incidence of Mycobacterium tuberculosis invades the human body depends not only on the quantity and toxicity of bacteria, but also depends on the body’s resistance of Mycobacterium tuberculosis. In the case of low immunity, M. tuberculosis invasion of host defense can not be system for the eradication