Angelica Six Yellow Decoction caused by high-dose glucocorticoid adverse clinical observation.docVIP

 PAGE \* MERGEFORMAT 5 Angelica Six Yellow Decoction caused by high-dose glucocorticoid adverse clinical observation [Keywords:] Angelica Six Yellow Decoction; adrenal cortex hormones; adverse reactions Certain diseases often require large doses of adrenal cortex hormone therapy, and high-dose application of adrenal cortex hormones often cause more side effects, such as acne, infection, hyperglycemia, hypertension, hypokalemia, weight gain. I in the treatment of When a number of neurological diseases observed in the use of high-dose adrenocorticotropic hormone same time, plus six yellow soup with angelica can significantly mitigate their adverse reactions. are reported below. 1 Clinical data 24 patients from March 2007 -2009 Academy of Neurology in June hospitalized patients, diagnosed in 16 patients with multiple sclerosis, optic myelitis in 2 cases, 3 cases of acute spinal cord inflammation, chronic Guillain - Barre General sign in 3 cases. selected patients require large doses of adrenal cortex hormone therapy, male 16, female 8, aged 18 to 55 years old, in addition to neurological diseases, are not suffering from diabetes, hypertension and other diseases . Press to enter the test sequence number and check the patients were randomly divided into 2 groups of 12 patients. 2 treatment Control group: treated with intravenous methylprednisolone, 500 mg / d, 5 d after conjunction to oral prednisone, 40 mg / d, then weekly by 5 mg, until disabled. At the same time calcium carbonate plus clothing - vitamin D tablets 1.5 g / d and famotidine 40 mg / d, a total of 61 d. drugs Observer Group: Except the above method treatment, while taking six yellow soup Angelica (Angelica sinensis, Rehmannia glutinosa, Rehmannia, Scutellaria, Coptis, Phellodendron the 10 g, Radix Astragali 20 g), day 1. Intravenous methylprednisolone used decoction; oral prednisone dose when half of each herb, made Shuiwan taking of medication 61 d. 3 OUTCOME MEASURES Ob