Angongniuhuang on brain injury in rat brain regulating the synthesis of apolipoprotein E.docVIP

 PAGE \* MERGEFORMAT 10 Angongniuhuang on brain injury in rat brain regulating the synthesis of apolipoprotein E Study: Law Daiya Guang Xu Zhen Wang Yiwei Li Huang [Abstract] [Objective] To investigate the mechanism of traumatic brain injury treatment Angongniuhuang. [Method] to the brain injury in rats fed Angongniuhuang powder, using reverse transcription - polymerase chain reaction (RT PCR in rat brain after traumatic organization of apolipoprotein E mRNA were detected. by enzyme-linked immunosorbent assay (ELISA method for the determination of post-traumatic brain apolipoprotein E levels in cerebrospinal fluid. [Results] Angongniuhuang can significantly increase the trauma of apolipoprotein E mRNA in brain tissue expression and cerebrospinal fluid apolipoprotein E concentration. [Conclusion] Angongniuhuang traumatic brain injury in rats by increasing the brain of apolipoprotein E mRNA expression and synthesis of apolipoprotein E, which promote the repair of damaged nervous system . [Keywords:] Angongniuhuang, traumatic brain injury in rats, apolipoprotein, E mRNA Abstract: [Objective] To explore the effects of angongniuhuang pill on the synthesis of apolipoprotein E in brains of rats after traumatic brain injury. [Methods] Using reverse transcription polymerase chain reaction (RT PCR and enzyme linked immunosorbent assay (ELISA, the apolipoprotein E’s mRNA of contused brain tissue and the concentration of apolipoprotein E in CSF at different phases after traumatic brain injury were detected of rats fed with angongniuhuang pills. [Results] High expression of apolipoprotein E mRNA and high concentration of apolipoprotein E were found in rats fed with angongniuhuang pills compared with controls. [Conclusion] Angongniuhuang pills may increase the expression of apolipoprotein E mRNA in brains after traumatic brain injury, thus promote the synthesizing and secreting of apolipoprotein E. Keywords:: angongniuhuang pill, rats with traumatic brain inju