Anti-aging tablets on aging on learning and memory and free radical metabolism.docVIP

 PAGE \* MERGEFORMAT 13 Anti-aging tablets on aging on learning and memory and free radical metabolism Study: Cold Xiaoxia Tao Tao Pan Yongming Shou Qi Yang Qing Yang Yuwei Zhu Keyan Tse Chen Min-li [Abstract] observed anti-aging tablets on learning and memory in aging rats and brain free radical metabolism. [Method] 72 healthy Wistar rats were randomly divided into control group, model control group, anti-aging piece of high, medium and low dose group and the LDB group Shouwu life extension piece group. D galactose by subcutaneous injection of 100mg/kg, 49 days of continuous modeling, the aging rat model, modeling the medication group were given medicines at the same time, observation Rats normally and body weight change, water maze spatial learning and memory ability, and determination of free radicals in brain metabolism of SOD, MDA, GSH Px, Na + K + ATPase, Ca + + Mg + + ATPase, NO and TChE change. [results] and the blank control group, the model control group body weight growth rate decreased (P lt;0.01, in brain tissue SOD, Na + K + ATPase, Ca + + Mg + + ATPase and GSH Px activity decreased, MDA, NO and TChE were significantly increased, the water maze test to explore the path and Tuning latency increased significantly. given different doses of anti-aging film, Liu Wei Di Huang Wan and Shouwu life extension piece, we could significantly improve the aging body weight growth rate, increased brain SOD, Na + K + ATPase, Ca + + Mg + + ATPase and GSH Px activity, significantly reduced MDA, NO content and TChE activity, reduce the aging rats in the water maze test to explore the path and find a station latency. [Conclusion] The anti-aging tablets can improve learning and memory ability of aged rats, enhance memory function, and delay brain tissue caused by free radical lipid peroxidation, anti-aging mechanism of inhibiting lipid peroxidation processes. [Keywords:] anti-aging tablets, learning and memory, free radical metabolism, acetylcholinesterase