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Atomic absorption spectrometry on Danshen injection of total sodium content
PAGE \* MERGEFORMAT 9
Atomic absorption spectrometry on Danshen injection of total sodium content
Of: Liwen Chun, Wen-Liang Liu, Sun Yonghui
[Abstract] Objective To determine the total Danshen injection of sodium content. Methods by flame atomic absorption spectrometry Danshen injection of total sodium content. The results of sodium chloride in the 0.5 ~ 10 mg / L range, the reading was good and the concentration linear relationship between the average recovery was 101.8%, RSD = 1.60%. Conclusion The method is simple, rapid, accurate, and can be used as quality control of the product.
[Keywords:] flame atomic absorption spectrometry, Danshen injection, determination, sodium
Keywords:: Flame atomic absorption spectroscopy, Danshen injection, content determination, Na
Extracellular sodium is to maintain an important component of osmotic pressure and capacity of sodium chloride for the treatment of extracellular fluid loss, dehydration and the diuretic, gastroenteritis caused by the sodium loss. Can be oral or intravenous. Generally fewer adverse reactions, not proper application may have high blood pressure, headache, dizziness, weight gain, appear or aggravate edema, accelerated heart rate, chest tightness, shortness of breath, wheezing and other lung. Currently, many agents contain sodium injection, especially in traditional Chinese medicine injection, but in the preparation process will introduce some of the sodium salt, none of the standard in quality control have on the salt, the traditional Chinese medicine injections is basically sodium content unknown, this drug safety in clinical use and has some hidden dangers. The test designed to establish a traditional Chinese medicine injection method in the determination of sodium in order to protect the safety of clinical medicine.
An instrument and reagent
PE-3300 atomic absorption spectrophotometer (USA); sodium hollow cathode lamp (Beijing Nonferrous Metal Research Institute), Mettler A
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