B cell non-Hodgkin lymphoma tumor CD22 antigen expression and clinical significance.docVIP

 PAGE \* MERGEFORMAT 14 B cell non-Hodgkin lymphoma tumor CD22 antigen expression and clinical significance Of: Zhang Dongsheng Dingyalisu Huck Jiang Zhong-Jun Xia Li Zhiming Lin Xubin [Abstract] [Objective] The detection of CD22 antigen in non-Hodgkin’s lymphoma tumor tissue expression of CD22 antigen in the initial non-Hodgkin’s lymphoma tumor tissues and clinical pathological characteristics. [Methods] Immunohistochemistry used to detect B-cell non-Hodgkin’s lymphoma tumor antigen expression CD22, CD22 antigen expression analysis of tumor tissue and clinicopathological characteristics of the relationship. [results] CD22 antigen in B cell non-Hodgkin’s lymphoma tumor expression mainly seen in the cytoplasm and cell membrane. the whole group of 21 patients, the positive rate of 100.00% (21/21), strongly positive (+++) rate of 14.29% (3 / 21), moderate positive (+ +) rate of 33.33% (7 / 21), weakly positive rate (+) 52.38% (11/21). CD22 expression and histological subtypes, sex, age and other clinical and pathological characteristics no significant correlation. [Conclusion] CD22 antigen in B cell non-Hodgkin’s widely expressed in lymphoma, can be used immunohistochemical methods to detect, the method is simple, there are certain clinical application; B cell non-Hodgkin’s lymphoma CD22 expression and clinical pathological characteristics need further study. [Keywords:] non-Hodgkin’s lymphoma; CD22 antigen; Immunohistochemistry Abstract: [Objective] To examine the CD22 antigen expression in B cell non-Hodgkin’s lymphoma (NHL) tissues and investigate its relationship with clinicopathological characteristics. [Methods] CD22 antigen expression in B cell NHL tissues was detected with immunohistochemistry staining. The correlation between CD22 expression and clinicopathological characteristics was analyzed. [Results] CD22 antigen was detected in B cell NHL tissue section by immunohistochemistry staining. The positive staining particles were located in cyto