Chinese and Western medicine treatment of gastroesophageal reflux disease progress.docVIP

 PAGE \* MERGEFORMAT 12 Chinese and Western medicine treatment of gastroesophageal reflux disease progress [Keywords:] GERD cure gastric acid suppression Hp drop out of harmony Gastroesophageal reflux disease (gastroesophageal reflux disease, GERD) is due to stomach and duodenal contents into the esophagus caused by anti-A group of clinical symptoms and esophageal tissue damage. Mainly as heartburn, regurgitation, chest pain three major symptoms. Acid (alkaline) reflux esophageal mucosal damage as a result of reflux esophagitis (reflux esophagitis, RE) [1]. Endoscopic observation of esophageal mucosa by whether there is damage, can be divided into endoscopic-positive GERD (ie RE) and endoscopy-negative GERD, the latter also known as non-erosive reflux disease (nonerosive refluxdisease NERD). RE endoscopic examination can be diagnosed and to evaluate the degree of esophagitis, as well as the existence of Barrett’s esophagus (BE). The Asia-Pacific region held in Singapore Digestive Disease Week of academic discussion and adopted by the Asia-Pacific GERD consensus that endoscopy is the gold standard for diagnosis of NERD. 1 / 3 of GERD patients have esophageal mucosal damage can be detected by conventional endoscopy [2]. More complex the pathogenesis of GERD has not yet entirely clear. In recent years, with the medical profession in-depth study of gastroesophageal reflux disease, treatment achieved good effect. A Western medical treatment Acid suppression therapy is the leading disease measures, generally divided into the initial treatment and maintenance therapy. In the initial treatment, acid-suppressing agent to proton pump inhibitor (PPI) as the preferred drug, omeprazole, rabeprazole, and esomeprazole is the most commonly used proton pump inhibitors, can rapidly relieve symptoms , but also reduce the reflux material damage to the esophageal mucosa, especially for erosive esophagitis associated with patients is to consolidate efficacy of maintenance therap