Chuan-ping compound preparation of the quality of screening analysis of ephedra herbs.docVIP

 PAGE \* MERGEFORMAT 13 Chuan-ping compound preparation of the quality of screening analysis of ephedra herbs Authors: HUO Wuzhen, WU Yan-Hong, Xu-Jiang Yuan, Li Yuan Xin, ZHU Sheng-shan [Abstract] Objective of the number of producing the quality of different batches of analysis and comparison of Ephedra herbs to identify issues in line with the needs of Ephedra herbs to ensure the stability and quality control agents efficacy, and quality control of the drug detection methods. Methods thin-layer method herbs preliminary screening method using liquid inter-epimer of the two ingredients ephedrine, pseudoephedrine, for determination. The results from different areas in different batches of medicinal Ephedra Ephedrine and pseudoephedrine content in quite different levels of ephedrine and pseudoephedrine are not proportional to the relationship. Conclusion According to TCM syndrome differentiation theory, the use of ephedra prescription medicines should be selected according to different needs of different areas of ephedra. The experiment through the systematic study of the methodology, the established HPLC method is simple, stable, exclusive, repeatable characteristics, can be used for medicinal herbs and products containing ephedra ephedrine compound preparation of quality control. [Keywords:] ephedra ephedrine pseudoephedrine Quality Control Chuan-ping compound preparation of traditional Chinese medicine development in Guangdong College of Pharmacy Institute of independent research and development of new drugs, indications of bronchial asthma, asthmatic bronchitis. Fong main drug ephedra, with divergent cold and disseminating the role of reduced lung and anti-asthmatic cough. According to modern pharmacological research, the main active ingredient is ephedrine, ephedra, has excited the respiratory center and the relaxation of bronchial smooth muscle to relieve bronchospasm role in [1]. In the study found that ephedra ingredients in accordance with ‘The 2005