Cirrhosis of liver transplantation perioperative pulmonary hypertension research.docVIP

 PAGE \* MERGEFORMAT 9 Cirrhosis of liver transplantation perioperative pulmonary hypertension research Around the world, end-stage liver disease is one of the greatest challenges facing mankind; in the United States ,45-55-year-old crowd, with end-stage liver disease is the third leading cause of death; China has nearly 140 million hepatitis B virus carrier persons, each with more than 1 million development of cirrhosis of the liver, cirrhosis of the liver has become second only to cardio-cerebral vascular diseases and malignant tumors of the major diseases, the number of cases the death of Gastroenterology about the number of cases of non-cancer deaths, 70% ~ 80%. January 31, 2006 organ acquisition and Transplantation Network (The Organ Procurement and Transplantation Network, OPTN) announced the United States, 257 transplant centers have been completed 75,532 cases of liver transplantation (1998 to January 31, 2006); the end of 2005 China has the completion of more than 8000 cases of liver transplantation, only a year in 2005 of about 3000 cases of liver transplantation purposes. In foreign countries, each year about 60,000 cases of liver transplants, of which 70% can achieve long-term survival more than 5 years in the domestic advanced liver transplant center has its therapeutic effect at or close to this level. In China, liver transplantation has become a treatment for conventional means of end-stage liver disease [1], while the advanced cirrhosis of the liver is the most important indications for liver transplantation. But how to improve the perioperative liver transplantation in cirrhotic patients with survival rates are still troubled by medical problems at home and abroad; Many studies have confirmed that early death in liver transplant cases, circulatory failure due to a larger proportion of deaths [2,3] , while the combined perioperative patients with liver cirrhosis appear pulmonary hypertension (pulmonary hypertension, PH) is affecting the surviv