Compound Xingnaotong Optimization of particle extraction.docVIP

 PAGE \* MERGEFORMAT 9 Compound Xingnaotong Optimization of particle extraction [Keywords:] compound Xingnaotong particle Abstract: Objective: Optimization by orthogonal test compound Xingnaotong particle extraction process. Methods: L9 (34) orthogonal experimental method in order to tanshinone Ⅱ A, Chuanxiong, Amomum villosum volatile oil, alkaloids bile Southern Star as an indicator of leaching of volatile oil extraction respectively, ethanol extract, water extraction process optimization options, examining the various factors impact. Results: Chuanxiong, Amomum villosum optimum extraction of volatile oil of herbs plus 10 times the amount of water-soaked after 2h reflux extraction 6h; Danshen ethanol extract the optimum amount for each increase of 10 times the 90% ethanol was extracted three times, 1.5h / times: water extraction to determine the best process for the A2 B2 C3, that is 20 times the amount of herbs plus boiling water 2 times, each time 1.5h. Conclusion: The results for the compound Xingnaotong particle extraction process to provide scientific experimental basis for the determination. Keywords:: compound Xingnaotong particle; Extraction Process Compound Xingnaotong particles from Salvia, gall Southern Star, Chuanxiong, Amomum drugs such as composition, with blood stasis, qi analgesic effect. Primarily for the treatment of coronary heart disease, angina, and other Qi stagnation blood stasis card. Fang Chuanxiong, Amomum villosum volatile oil, tanshinone Ⅱ A, water-soluble alkaloids are the main active ingredient. According to the nature of the active ingredients separately volatile oil extraction, alcohol extraction and water extraction technology research to improve product quality to ensure that the clinical treatment provide a scientific theory. An instrument and reagent 1.1 Instrument BIO-TEK HPLC535, KQ-500E-based medical ultrasonic cleaner (Kunshan Ultrasonic Instrument Co., Ltd.), electronic balance (FAll04), rotary evaporator (Sh