Congenital cystic adenomatoid malformation of the lung II in 1 case and review of literature.docVIP

 PAGE \* MERGEFORMAT 10 Congenital cystic adenomatoid malformation of the lung II in 1 case and review of literature Of: DONG Chun Ge, Hai Hung Cheng, Wu Liang, the top three cattle, Chen Guorong [Abstract] Objective: To investigate the congenital cystic adenomatoid malformation of the clinical manifestations, pathological type, prognosis and disease related factors. Methods: The clinical data, through the autopsy, the gross and microscopic observation of lung morphological changes, and by immunohistochemical EnVision two-step detection of lesions of the lung tissue of cytokeratin 7 (CK7, thyroid transcription factor 1 (TTF-1 expression and literature review. Results: Lung volume increased significantly, section sizes clouds cysts. endoscopic single large cysts lined with ciliated columnar epithelium or pseudostratified ciliated columnar epithelium and small cysts lined with simple cuboidal epithelium, a large number of adenomatous hyperplasia of the formation of small cyst-like structure. cysts can be seen between the relatively normal lung lobules. cyst lining epithelial cells CK7 (+). wall part of the columnar epithelium, cuboidal epithelium cells TTF-1 (+. Conclusion: The congenital cystic adenomatoid malformation of the lung prognosis related to pathology, CK7’s expression, TTF1 expression can be used as part of congenital cystic adenomatoid malformation of the diagnosis of type . [Keywords:] cytokeratin, thyroid transcription factor, cystic adenomatoid malformation of the lung, congenital Lung tissue of children with congenital cystic adenomatoid malformation (congenital cystic adenomatoid malformation of lung, CCAM) II-type clinical rare, mostly to the fetus and newborn, often accompanied by disorders of lung development and lung function was low, there may be fetal edema , neonatal breathing difficulties, or no symptoms, it can be a fetus or newborn lethal disease. is to review the literature 1 case of autopsy specimens were reported as foll