Cordyceps extracts from different areas of the Comparative Study of Pharmacodynamics.docVIP

 PAGE \* MERGEFORMAT 3 Cordyceps extracts from different areas of the Comparative Study of Pharmacodynamics [Abstract] Objective To study the origin of the pharmacodynamic effects of Cordyceps extracts. Methods xylene-induced mouse ear swelling method to measure the weight of ear pieces; using colorimetric analysis of mice liver glycogen after swimming, as well as determination of serum lactic acid content in mice after injection of Congo red Congo red blood residue. The results in the role of anti-inflammatory and anti-fatigue effect of the Qinghai Cordyceps best to enhance phagocytosis of Tibet, Chinese caterpillar fungus with considerable effect. Conclusion Qinghai Cordyceps pharmacodynamics in some areas has a certain advantage. [Keywords:] Cordyceps extract; anti-inflammatory; anti-fatigue Studies have shown that Cordyceps has anti-inflammatory, antioxidant, immune regulation, and multiple roles. In this paper, the different origin of Cordyceps extract pharmacodynamics make a comparative study of quality assessment for genuine medicines to provide experimental basis. Are reported below. 1 Materials 1.1 Drugs in Qinghai and Tibet, Chinese caterpillar fungus Cordyceps, collected from Qinghai Province Nangqian County, Nagqu Maqê n and Tibet region, Sichuan Province, Sichuan Province Institute for Drug Control Cordyceps commissioned to provide samples of Pharmaceutical and Biological Products by the traditional Chinese medicine room identified as ergot fungus Division Cordyceps fungus parasites in the bat-e Branch of the child seat on the insect larvae and larval body complex. Cordyceps extract of methanol extract, three kinds of Cordyceps extract recoveries were 19.6%, 23.3% and 16.1%. Gavage dose of the recovery rate calculated by adding the amount of saline extract of Cordyceps, the large and small doses the equivalent of Pharmacognosy 4 g / kg and 2 g / kg, ultrasound Suspension. Mice administered volume of 0.1 ml/10 g body weight. Congo red, hepatic