Danzhi Capsule Optimization of Extraction Process.docVIP

 PAGE \* MERGEFORMAT 14 Danzhi Capsule Optimization of Extraction Process [Abstract] Objective To optimize the best Danzhi Capsule extraction process. Methods directly extracted by steam distillation of Paeonol Moutan ingredients, then mix the dregs and other Smell, select the three factors and three orthogonal experiments to extract rate of the polysaccharide, as index paeoniflorin, the number of extraction, extraction time, amount of water to conduct investigations. results to determine the optimal extraction process as follows: add 10 times the amount of water extracted three times, each 1.5 h . Conclusion The process can be used as Danzhi Capsule extraction process, the method is simple and stable. [Keywords:] Danzhi Capsule, extraction process, orthogonal design DOI: 10.3969/j.issn.1005-5304.2011.02.022 CLC number: R283.5 Document code: A Article ID :1005 -5304 (2011) 02-0055-03 Optimization of Extracting Process of Danzhi Jiangtang Capsule JIANG Lei1, 2, WANG Yong-zhong2, HAN Yan-quan2 (1.Anhui College of TCM, Hefei 230031, China, 2.The First Affiliated Hospital of Anhui College of TCM, Grade 3 Laboratory of TCM Preparation, State Administration of TCM, Hefei 230031, China) Abstract: Objective To optimize the extracting condition for Danzhi Jiangtang Capsule. Methods With the wet distillation to extract the paeonol in moutan cortex, then admix its gruffs and other medicinal substances, orthogonal design with three factors and three levels was used and taking the rate of paste, amont of polycose and the content of paeoniflorin as the standards to study the extracting frequency, times and amount of water. Results The optimized extracting condition was to add water with 10 folds, extract for 1.5 hour and extract 3 times. Conclusion The optimized process is convenient and stable. Keywords:: Danzhi Jiangtang Capsule, extracting process, orthogonal design Danzhi Capsule (compound preparations) from Paeonia suffruticosa, to yellow,