Different concentrations of sufentanil for intravenous analgesia in elderly patients.docVIP

 PAGE \* MERGEFORMAT 6 Different concentrations of sufentanil for intravenous analgesia in elderly patients [Keywords:] different concentrations; sufentanil; elderly patients; postoperative analgesia Lower limb surgery in elderly patients, due to pain stimulation, can cause heart rate, blood pressure and other cardiovascular reactions, increased risk of perioperative incidence. Sufentanil for the opioid receptor agonist, analgesic potency is fentanyl 5 to 10 times the area of postoperative pain in a significant advantage. In this study, flexible and convenient for patient-controlled intravenous analgesia (PCIA) will compare the two kinds of low concentrations of 1.5 and 2.0 g / kg of Shu fentanyl PCIA lower limb surgery in elderly patients with analgesic and sedative effects and adverse reactions. 1 Materials and Methods 1.1 General information on 45 patients aged 67 to 85 years, ASA ~ patients undergoing elective lower limb surgery, 25 males and 20 females, of which 33 patients with hypertension, coronary heart disease in 18 patients with chronic bronchitis 8 cases. randomly divided into two groups, group, 22 cases, group of 23 patients. All patients were asked to insert the LMA after the sciatic nerve block and lumbar plexus nerve block. anesthetic effect of sound, operation duration 1 3 h. the two groups in age, weight, operative time was not significant (Pgt; 0.05). 1.2 Methods PCIA group formula: Sufentanil 1.5 g / kg +0.9% sodium chloride solution, 100 ml, group: Sufentanil 2.0 g / kg +0.9% sodium chloride solution, 100 ml. Two Hu Yang a one-time trace are used analgesia pump. surgery began at the end of infusion to 2 ml / h continuous infusion rate, PCA amount of 0.5 ml / second, the minimum interval of 10 min. 1.3 Assessment of results after 2,4,8,24,48 h were recorded dynamic VAS score and Ramsay sedation score, record the time of the pulse oxygen saturation (SpO2), respiratory rate (RR), nausea and vomiting score. patients c