Disease and syndrome animal model evaluation and prospects.docVIP

 PAGE \* MERGEFORMAT 20 Disease and syndrome animal model evaluation and prospects [Abstract] animal models of disease and syndrome from the preparation and evaluation of two major aspects of the model of the disease and syndrome we reviewed. On the disease and syndrome model significance, model preparation, disease and syndrome types of options, making model animal selection, the choice of modeling factors and other aspects of the model evaluation methods and evaluation standards, etc. were also discussed. that model of disease and syndrome problems, and make recommendations accordingly. [Keywords:] disease and syndrome model, model preparation, evaluation methods Abstract: This article summarized the study progress in two main aspects of establishment and evaluation methods of integration of disease and syndrome animal models, elaborated the significance of the research of integration of disease and syndrome animal models; the selection of Chinese medicine syndromes, the dieases , the animals for making models, and the facts for making models.Manifest the methods and standards for evaluating the models.Meanwhile point out the problems and give some ideas on the direction of research in the future. Keywords:: integration of disease and syndrome model; establishment method; evaluation criterion “Disease and syndrome” Western diseases, animal models of both the characteristics, but also the characteristics of TCM, it will help Pharmacology research and evaluation of efficacy of Chinese medicine is conducive to a more comprehensive and objective understanding of the scientific connotation of traditional Chinese medicine for the pathophysiology of diseases and syndromes characteristic changes between, but also show a greater advantage. In recent years, the nature around the syndrome, from clinical research to animal experiments, from seeking a single “card” of the specific indicators to the study of a disease and syndrome Syndrome of objective ind