Diuretics in the treatment of hypertension in the position of.docVIP

 PAGE \* MERGEFORMAT 6 Diuretics in the treatment of hypertension in the position of [Keywords:] hypertension; diuretics Nearly half a century, diuretics have been the treatment of high blood pressure plays an important role, long-term clinical practice shows that low-dose diuretics in the application less adverse reactions, more safe, and effective for most patients with hypertension, and difficult to produce resistance medicinal properties, can stand alone as a first choice for drug treatment of mild hypertension, can also be combined with other drugs the treatment of moderate and severe hypertension. The U.S. JNC-VII (2003 years) hypertensive patients without complications claim to diuretics as the preferred drug. More types of diuretics, including thiazide diuretics for its role in relaxation, the role of a long time, and the advantages of fewer adverse reactions but are most commonly used. The primary role of a diuretic The antihypertensive effect of diuretics has always been that people recognized. Some large-scale clinical trials (such as SHEP, STOP, etc.) results show that the antihypertensive effect of diuretics in the affirmative, the elderly, obesity and hypertension in patients with heart failure was more evident. In the analysis of several clinical trials showed that compared with other antihypertensive drugs, diuretics for systolic blood pressure (SBP), the average blood pressure is slightly lower rate, for diastolic blood pressure (DBP) is superior to α by the magnitude of the step-down Body blockers and β -blockers, and adrenergic receptor agonists (ARB) is similar to but less than ACE inhibitors and calcium channel blockers (CCB). Anti-hypertensive drugs to treat high blood pressure combined with the primary means of about 82% of patients need to use more than two kinds of drugs, 51% of patients need more than three kinds of drugs. Diuretics is a recognized and effective first-line anti-hypertensive drugs. Recommended combination therapy