Domestic and imported Docetaxel Treatment for Metastatic Breast Cancer.docVIP

 PAGE \* MERGEFORMAT 7 Domestic and imported Docetaxel Treatment for Metastatic Breast Cancer [Keywords:] metastatic breast cancer; docetaxel; made; imports To docetaxel-based combination chemotherapy in the treatment of metastatic breast cancer and better (1), is the primary treatment of metastatic breast cancer recommended method. However, docetaxel at home and abroad have different manufacturers, domestic and imports of docetaxel in the price difference is large, the efficacy and toxicity of whether there are differences to be studied. The author uses domestic and imported docetaxel based combination chemotherapy in the treatment of metastatic breast cancer patients and another made a comparative efficacy and toxicity. 1 Materials and Methods 1.1 The object of study chosen from February 2007 to February 2010 in our hospital by the B-, X ray, CT and MRI and bone scan diagnosed 40 patients with metastatic breast cancer, aged 38 to 71 years old, divided into observation group and control group patients were .40 KPSgt; = 70 points, is expected to survive more than 3 months and nearly a month without line radiotherapy, chemotherapy, blood, liver function, renal function and ECG were normal. Observer Group 20 patients, aged (49.2 + -12.7 years), in which a transfer of 7 cases, 8 cases of transfer of two, three or more transfers in 5 cases. control group of 20 patients aged (50.4 + -10.9 years), a transfer of in 5 cases, two metastasis in 9 cases, 3 more than the transfer of the 6 patients. two sets of data were generally not significant and comparable (Pgt; 0.05). 1.2 method two groups were started 1 d before administration of oral dexamethasone (Fu Jen Catholic medicine, Zhunzi 8 mg, 2 times / d, used in conjunction 3 d; Xeloda (Roche, Zhunzi ) per 1 250 mg/m2, sooner or later, 2 times, meal 30min oral chemotherapy for taking 2 w. after bolus 5-HT3 antagonist gastrointestinal reaction control; given glucocorticoid pretreatment