Domestic quetiapine fumarate treatment of senile dementia and perphenazine control study of psychiatric symptoms.docVIP

 PAGE \* MERGEFORMAT 9 Domestic quetiapine fumarate treatment of senile dementia and perphenazine control study of psychiatric symptoms Author: Written by Wang Hui Shi Yan Li-Bo Wang Chunyan [Keywords:] dementia, mental disorders, quetiapine, perphenazine China’s urban residents over 65 years the prevalence of dementia more than 6%, and increased with age and doubled up (1). Almost all patients have manifestations in the course of behavioral and psychological symptoms of dementia in the spirit of the act commonly known as symptoms (BPSD, of which 24% of elderly patients with dementia to function-based mental disorders. This is not only the social function of the patient himself severely affected, but also to his guardian care of the larger difficulties, but also greatly increased our social burden and economic burden. This paper made with perphenazine quetiapine fumarate tablets in the treatment of Alzheimer’s efficacy and safety of BPSD were observed. 1 Subjects and methods 1.1 Object Our hospital from March 2000 to March 2008 58 patients received in hospital. Inclusion criteria: in line with China Classification and diagnostic criteria of mental disorders 3rd edition (CCMD 3 Alzheimer’s disease or vascular dementia diagnostic criteria , Mini Mental State Examination lt;24 points, with manic state (irritation of the increased emotional high, and exaggerated paranoia, bulimia, sexual interest increased, meddlesome, hallucinations, delusions, apathy, depression or euphoria, anxiety, fiction , eat or sleep disorders, psychiatric symptoms such as personality change, while the exclusion of other comorbid psychiatric disorders or with severe physical illness. into the group of patients before obtaining the informed consent of the custodial family .58 patients, 30 males, females 28 patients were randomly divided into 2 groups, 29 cases of quetiapine group, the average age (66.2 + -7 years, mean disease duration (12 + -6 months, perphenazine group of