Effect of taurine on liver cell injury in Progress.docVIP

 PAGE \* MERGEFORMAT 20 Effect of taurine on liver cell injury in Progress Keywords: taurine; liver cell injury; cell protection; cirrhosis of the liver Taurine, also known as 2 - aminoethanesulfonic acid, is a transformation from the sulfur-containing amino acids from the β-amino acids, and free the human body exist in a variety of organizations, is the most abundant animals free amino acids. Taurine as a precious Chinese medicine “bezoar” active ingredients, it has heat, analgesic, sedative, anti-convulsive, anti-platelet aggregation, anti-arrhythmia, lower blood pressure, lowering blood sugar, increase immunity, complement bile, nourish the liver and detoxification, regulating vascular tone, correct amino acid imbalances in the body a variety of pharmacological effects. More and more evidence that taurine has a wide range of biological effects, blood, immune, reproductive system, visual function need to taurine, it also as a central inhibitory neurotransmitter regulating central nervous system. Study found that taurine is through regulation of cell calcium stability, scavenging oxygen free radicals, inhibit lipid peroxidation and maintaining cellular osmotic pressure, cell membrane stability and a variety of mechanisms play a role [1,2]. The liver is the main site of taurine synthesis is also a major target organ effects of taurine, taurine on the liver injury has become a research hot spot. In recent years, the author is now on the protective effect of taurine on liver injury in the research are reviewed. 1 Effect of taurine on lipid peroxidation of liver injury in rats Liver lipid peroxidation is an important mechanism of liver injury, harmful substances in liver tissue by attacking cell membrane lipids, causing lipid peroxidation to form lipid peroxides, which is more important to malondialdehyde (MDA). Lipid peroxidation not only reactive oxygen species into active chemical agents, but also by chain or branched-chain reac