Effects of losartan combined with indapamide in type 2 diabetes and left ventricular hypertrophy in hypertension.docVIP

 PAGE \* MERGEFORMAT 7 Effects of losartan combined with indapamide in type 2 diabetes and left ventricular hypertrophy in hypertension [Keywords:] Losartan; indapamide; diabetes, type 2; hypertension; left ventricular hypertrophy Because patients with hypertension and diabetes incidence of cardiovascular events and mortality are significantly higher than that in patients with hypertension or diabetes, treating diabetes and high blood pressure so active is very important. I January 2006 -2008 losartan in January combined with indapamide sustained release tablets in the treatment of type 2 diabetes and hypertension in patients with left ventricular hypertrophy in 125 patients observed antihypertensive effect and the impact on left ventricular hypertrophy, are summarized below. 1 Clinical data 1.1 General information and type 2 diabetes mellitus patients with hypertension and left ventricular hypertrophy 125 patients were randomly divided into control group and observation group, treatment group 2 compared to the situation in general in Table 1. Treatment: control group was given losartan 50 mg (Hangzhou MSD Pharmaceutical Co., Ltd., batch number 09196), day 1; observation group was given losartan 50 mg, day 1, in parallel with indapamide sustained release tablets (Servier Pharmaceutical Co., Ltd. Tianjin , lot 9C1295) 1.5 mg, day 1 .2 group of patients observed for 20 weeks. monitoring during the treatment of liver and kidney function, electrolytes, and electrocardiogram. 1.2 Monitoring Indicators (1) 24 h ambulatory blood pressure measurement. Using non-invasive portable blood pressure monitor (ABPM-04 type, Beijing Merrill Lynch) in the treatment of 20 weeks before and after treatment were measured 24 h ambulatory blood pressure. Cuff fixed in the left upper limb, and the day 1 of each measured 30 min; night measured every 60 min 1. effective number of measurements to be 85%, or need to repeat measurements. measured data: 24 h level Table 1 Comp