Experimental Study of Lung Cancer.docVIP

 PAGE \* MERGEFORMAT 8 Experimental Study of Lung Cancer On: Sun Dejun Ma Ying Wang Weisheng Tangfang Yong Ren Liming with [Abstract] Objective To investigate patients with lung cancer tumor markers used in the early diagnosis improve the diagnostic rate of combined detection and monitoring of the disease based on changes in value. Methods 293 cases of lung cancer patients aged 38-81 years, male to female ratio of 3:1, were to Since December 2002 to November 2006 our hospital and hospital patients, the NSE, D-dimer, CEA, IL-6R level of detection, the 293 patients were divided into: 98 cases of early lung cancer, advanced lung cancer group of 195 patients, non-small cell lung cancer (non-small cell lungcancer, NSCLC group of 202 patients, small cell lung cancer (small cell lung cancer, SCLC group of 91 cases, 138 cases of patients before treatment, after treatment, 155 cases, healthy people choose 300 cases as normal as the control group, aged 35 to 80 years old, male to female ratio of 3:1, by ELISA on 293 blood samples of patients with lung cancer neuron-specific enolase (NSE, carcinoembryonic antigen (CEA, IL Su -6 receptor (IL-6R, D-dimer (D-Dimer test four levels. Results of early lung cancer CEA, NSE, IL-6R were higher than in healthy controls (P lt;0.01, while the D- Dimer in early stage lung cancer patients compared with healthy control group was not significant (Pgt; 0.05, advanced lung cancer group CEA, NSE, IL-6R, D-Dimer levels were higher than those of early lung cancer group (P lt;0.01, NSCLC group CEA, IL-6R, D-Dimer levels were higher than the SCLC group (P lt;0.01 less than the SCLC group and NSE before treatment CEA, NSE, IL-6R were higher than those after treatment (P lt;0.01. positive diagnostic rate for the four simultaneous detection of 81.6%, NSE, CEA, IL-6R three test 78.2%, NSE, CEA two tests 61.8%, NSE 48.5% of a test. Conclusion CEA, NSE, IL-6R, D-Dimer IV items than the combined detection rate of single diagnostic test positive,